Ohio State - Nationwide Children's Hospital - Research For Muscle Biology and Disease

Tom Best, M.D., Ph.D., FACSMTom Best , M.D., Ph.D., FACSM
Professor of Family Medicine
Pomerene Chair of Primary Care
Director of the Division of Sports Medicine

The Ohio State University
OSU Sports Medicine
Martha Morehouse Medical Plaza
2050 Kenny Dr.
Columbus, OH 43221

Phone: (614) 293-3600
Fax: (614) 293-4399
Email: tom.best@osumc.edu

Education & Training:
University of Windsor, 1984 B.S. & M.S. in Kinesiology
University of Western Ontario, 1988 M.D.
Duke University, 1992 Ph.D. in Biomedical Engineering
University of North Carolina at Chapel Hill, 1995 Residency in Family Medicine and Sports Medicine Fellowship

Research Interest:
Dr. Best is Professor and Pomerene Endowed Chair in the Department of Family Medicine. He is the Director of the Division of Sports Medicine and Co-Medical Director for the OSU Sports Medicine Center. His research focuses on the mechanisms for stretch injury and repair of skeletal muscle. A combination of clinical (using methods of motion analysis) and basic science studies are aimed at improving methods of treatment and prevention of muscle injury. Bench investigations focus on the role of neutrophils in injury and repair. The role of calcium and stretch-activated channels and their relationship to injury and adaptation of skeletal muscle following eccentric exercise are a recent line of study. The utility of massage to regulate inflammation and repair is another current focus of Dr. Best’s lab.

Selected Publications:

  • Butterfield TA, Haq F, Agarwal S, Zhao Y, Best TM. Cyclic Compressive Loads Improve Recovery And Reduce Myofiber Damage After Eccentric Contractions. Med Sci Sports Exer 40(7): 1289-1296, 2008.
  • Butterfield TA, Best TM. Stretch Activated Ion Channels Are Essential for Functional Adaptations Following Repetitive Eccentric Loading in Skeletal Muscle. Med Sci Sports Exer 2009 Jan 5 [Epub ahead of print].
  • Haas C, Best TM, Wang Q, Zhao Y. In Vivo Passive Mechanical Properties of Skeletal Muscle Improve With Massage-Like Loading Following Eccentric Exercise. J Biomech. 2012 Oct; 45(15): 2630-2636.
  • Gharaibeh B, Huard J, Best TM. Stems Cells, Angiogenesis and Muscle Healing – A Potential Role
    in Massage Therapies? Br J Sports Med 2012 Oct. (Accepted).
  • Haas C, Butterfield TA, Zhao Y, Ziaoli Z, Jarjoura D, Best TM. Dose-dependency of massage-like
    compressive loading on recovery of active muscle properties following eccentric exercise: rabbit
    study with clinical Relevance. Br J Sports Med 2012 June. [Epub ahead of print]
  • Haas C, Butterfield TA, Abshire S, Zhao Y, Zhang X, Jarjoura D, Best TM. Massage Timing Affects Postexercise Muscle Recovery and Inflammation in a Rabbit Model. Med
    Sci Sports Exerc.
    2012 Dec. [Epub ahead of print]