Syllabus – MVIMG 747 Neuromuscular Biology and Disease, Spring 2012
Thursdays 4-5pm, HRLI 165
Instructors: Arthur Burghes, PhD and Denis Guttridge, PhD
• WEEK 1 - Introduction to neuromuscular disorders DMD to ALS - John Kissel, MD
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• WEEK 2 - Pathology of neuromuscular disease: muscle and nerve - Zarife Sahenk, MD, PhD
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• WEEK 3 - Development of the motor neuron and sensory neuron – Christine Beattie, PhD
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• WEEK 4 - The structure of the NMJ (overview of electrophysiology) – Steve Kolb, MD, PhD
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• WEEK 5 - The development of skeletal muscle – POSTPONED |
• WEEK 6 - How to measure heart and skeletal muscle physiologically - Paul Jansen, PhD
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• WEEK 7 - Signaling pathways that regulate muscle mass – Denis Guttridge, PhD
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• WEEK 8 - The role of glycosylation in neuromuscular disorders - Paul Martin, PhD
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• WEEK 9 - Therapeutic strategies of motor neuron diseases: SMA and ALS - Arthur Burghes, PhD
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• WEEK 10 - Development of novel therapies for the dystrophies translation to the clinic – Jerry Mendell, MD
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