Center for Muscle Health and Neuromuscular Disorders - Ohio State University and Nationwide Children's Hospital

Trainee Poster Day 2008

Trainee Poster Session

In November of 2008, graduate students, postdoctoral fellows, residents, and staff from our muscle group came together and presented their work in our first annual trainee poster session. The event was held in the lobby of the Biomedical Research Tower on the campus of Ohio State and was accompanied with a reception. Over 30 posters were presented representing a diversity of muscle related topics, whose titles are shown below. 

  • Characterization and in vitro expansion of muscle progenitor cells for use in cell based therapies for muscular dystrophy
  • Characterization of mdx and mdx5Cv mouse models for application in the study of Duchenne muscular dystrophy treatment strategies
  • Cyclic compressive loading facilitates recovery following eccentric exercise
  • NF-kb – YY1 – mIR29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma
  • Single fiber isolation and pax7 immunofluoresence
  • Understanding the role of the cell junction protein claudin-5 in cardiomyopathy and heart failure
  • NF-kB functions as an inhibitor of post-natal muscle development
  • Genotype analysis predicts dilated cardiomyopathy in Beckers muscular dystrophy
  • FSHD candidate gene DUX4 causes in vivo myotoxicity
  • Evidence for the involvement of early insulin resistance in the development of cachexia in mice bearing colon-26 tumors
  • Evidence for metabolic inflexibility during atrophy of cardiac muscle in mice
  • Nitroxyl improves cardiac myocyte contraction independent of L-type Calcium current
  • Effect of Calcium binding properties of TnC on the rate of skeletal muscle tension redevelopment
  • Abnormal Calcium binding properties of the thin filaments caused by the cardiomyopathy mutation TnI R192H can be corrected through TnC mutagnesis
  • Neuronal nitric oxide synthase (NOS1) knockout mice exhibit a blunted force frequency response
  • Reversal of the cardiac dysfunction in neuronal nitric oxide synthase knockout myocytes by the nitric oxide donor SNAP
  • Generation of a new mouse model to help determine the therapeutic time-point for SMN replacement therapies: An update
  • Development and characterization of a transgenic mutant sod1 zebrafish model of ALS
  • CASK localizes to multiple subcellular fractions and plays an important function in skeletal muscle integrity
  • O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors
  • Myostatin inhibition by follastin gene therapy improves dystrophic symptoms in dy/dy mice
  • Transgenic overexpression of CT GalNac transferase (Galgt2) in skeletal muscle inhibits muscular dystrophy in a mouse model of limb-girdle muscular dystrophy 2D
  • IGF-1 rescues motor neuron toxicity in an in vitro stem cell-based model of ALS
  • Dynamic relaxation primarily determined by myofilament properties
  • A gene therapy strategy utilizing follastatin combined with micro-dystrophin dramatically improves force generation in mdx mice
  • Mechanical properties of atrial muscle preparations
  • Functional and molecular changes during development of compensatory hypertrophy
  • Eccentric contraction in mdx mice trabeculae
  • Transcriptional programming of embryonic and adult stem cells
  • Impact of hydroxyl radicals on calcium handling and myofilament sensitivity in isolated myocardium
  • Experimental targeted gene therapy for quadriceps muscle weakness for sporadic inclusion body myositis (sIBM) with implications for other neuromuscular disorders
  • Regulation of the splicing mechanism of MDM2 in response to DNA damage using a splicing competent minigene system
  • Biomechanical signals upregulate myogenic gene induction
  • Mouse Smn exon 7 C>T: A Smn2 like knock-in mouse model of Spinal Muscular Atrophy